Winfrey has the ear of presidents - Obama is the fifth
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The show in numbers
So how has Winfrey been such a success? Ten moments sum up her influence.
MAKES HER SEXUAL ABUSE CLAIM, 1986
THE WAGON OF FAT, 1988
MICHAEL JACKSON OPENS UP, 1993
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A troubled early life
- 1954: Born in Mississippi to a teenage mother
- 1960: Moved to inner-city Milwaukee
- 1967: Ran away from home
- 1968: Pregnant at 14 but lost the baby
- 1971: Moved to father in Nashville and earned a place at Tennessee State University, working part-time at a local radio station
- 1976: Anchored TV news in Baltimore
- 1983: Hosted morning show in Chicago
- 1985: Co-starred in The Color Purple
- 1986: Talk show renamed and goes national
ELLEN DEGENERES COMES OUT, 1997
American stand-up comedian, television host and actress Ellen DeGeneres came out publicly as a lesbian in an appearance on the show.
Winfrey's inspiration to other women has been much debated.
THE BIG CAR GIVEAWAY, 2004
TOM CRUISE ON THE SOFA, 2005
"It should have been an open goal for Tom Cruise but it became a train wreck."
JAMES FREY CONDEMNED, 2006
SOUTH AFRICA SCHOOL OPENS, 2007
Winfrey's Leadership Academy, near Johannesburg, was opened in 2007 at a cost of $40m (£25m).
Last year, the former matron of the school was cleared on charges of abusing girls there.
BACKS OBAMA, NOT CLINTON, 2007
STAR-STUDDED FAREWELL, 2011
"A clear part of her appeal has always been someone who collects star friends," says Deggans.
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